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April 20, 2011

Clean living: Kills ‘em dead every time

Here’s a bold statement, “Dirty up your act!”

I began to think about statistical analysis the other day and something one of my professors in Probability and Statistics said made him crazy, “Users of creative analysis, should not be licensed to carry calculators.”  It’s the idea that a set of data, say the amount of apples cancer patients eat in a year can predict the health benefits of apples for the rest of us, can be very enticing.  Finding out that this particular set of patients did not eat an entire bushel of apples every year, “unmistakably” leads us to the conclusion that they failed to protect themselves with that obvious anti-cancer wonder drug.  The problem with this kind of analysis is that we want it to predict that there are anti-cancer benefits to apples, and so it does.

Apples are nice, fresh (well, most anyway) and seem to scream “Health!”  It seems just a hop, skip and a few taps of the array key to conclusive proof  that apples are the anti-cancer weapon of the future. The stray facts that 60% of the study’s participants were addicted to dental X-Rays and the other 40% drank a dose of motor oil every day can be left pleasantly aside.

A great deal of “healthy living” advice is based on statistical analysis, or as I always suspect “creative analysis.”  We have become a nation of dutiful hand washers and vegetable eaters based on “scientific” analysis of health benefits from these noble pastimes.  And yet, quite mysteriously, cancer rates continue to increase, new and terrible infections are on the rise and there is a veritable epidemic of the need for anti-anxiety drugs.    I often wonder if the last is due to the failure of our current analyses to offer significant protection from the rest.

What started me on this line of thought, was the recent death of my sister from cancer.  She lived as about a healthy life as one could, resisting all forms temptation, working hard, sleeping well and remaining svelte her entire life.  And then I thought of my own first wife who gave up drinking, smoking and began to carefully watch her weight when we first had children, and then died of breast cancer shortly after out third son was born.  Or my brother in law who also gave up smoking, and severely limited his drinking about 15 years before he died of cancer.  Does that mean anything?  My professor would say the population sample is pitiful, and there was no possibility of significant factor development.  Ok, so “clean living” didn’t kill them?

He’d be right about significant factors, of course.  But continuing to press along this line of non-sensical reasoning let’s consider the human immune system.  It’s a very clever design.  Our immune systems function so well, not because they act like defenders behind impenetrable walls, but rather as Jonas Salk might say “because they let the bad guys in.”  It’s a system that does essentially the seemingly worst possible thing for the body it protects.  However, Earth is a planet where it’s impossible to maintain complete sterility.  The air, land,waters and every surface are teeming with organisms of every shape and size.  We can scrub and shower all day every day and we are still covered in germs, viruses and other microorganisms from head to toe.  Being well developed for Earth dwellers, our immune system welcomes these pesky invaders into the inner sanctum and then learns how best to destroy them. Because it doesn’t forget an enemy, it’s even more ready the next time.   So maybe we shouldn’t wash our hands, for fear of dumbing down our immune system?

However, subject that same amazing immune system to “creative analysis”  and  we would be soon be temped to scrap the whole works.  Without much math we probably can agree that just about everyone does get sick from time to time.  With 100% chance of getting sick sooner or later that failure rate looks pretty dismal, especially because we just can’t tell how many sicknesses were successfully fought off.  The “creative analyzer” may well assume zero diseases defeated.  Who could prove him wrong?

Which makes daily hospital-level sanitary precautions for everyone seem much less loony and has made hand sanitizers a best selling product.  The fact that we can’t tell if these sanitizers have any effect at all, and may well be the worst thing we could do, appears more like a protection value instead of a failure rate.  What is the cumulative effect of hand sanitizers, are they a viable alternative to a well tuned immune system?  Or is it better to fight disease on the inside?  That’s certainly not what the makers of hand sanitizers want to hear.

But nice, clean and scented hands are attractive, surely they belong in the “halls of health.”  Consequently children should never play in the dirt, people with diseases should be shunned and “Why don’t they sell hand-sanitizer in 55 gallon drums with wheels on the bottom?”

Statistics “prove” it all.  However, as someone who did pretty well in statistical and probability theory let me mention the familiar and well informed phrase from Benjamin Disraeli, “There are three kinds of lies: lies, damned lies, and statistics.”

One of the main problems with trusting statistical analysis is only the best studies include three crucial pieces of information; the “angle”, the “population” and the “standard of deviation.”  I have little doubt that most times these items of gobbledy-gook and mathematical michigas are invariably left filed in the back room of far away lands for the sake of “clarity.”

In this case the “angle” is the statisticians approach to the mass of raw data.  Every study has an angle, it’s both what made them look in the first place and the method they used.  In the anti-cancer apple case above, maybe the cause for the study was the stunning discovery of a possible link between cancer and the fruit, or maybe it was a grant from the Apple Growers of Oregon.  Either would have an appreciable effect on the method as well, wouldn’t it?  After all, which is more useful to the AGO, the amount of apples they did eat (god forbid!) or the ones they didn’t?

The population is important as well.  Was this a study of 2000 swarthy, balding, Croat asbestos handlers, or 20 elderly ladies from Chernobyl with rubber false teeth?  Even knowing the details of the population, for the most part it’s possible to prove just about any assertion with any population depending on the data you collect.  As in the same case above, “Goodness me, why would we ask about dental X-rays?”  The best fights over statistical analyses are always about what the study didn’t look at.

If there is one piece of information that should be included in every study it’s the Standard of Deviation.  Whether it’s “70% of doctors know that Camel filters provide the smoothest smoke” (the dead ones, anyway) or “90% of choosey mothers chose Jif” (sample taken in the town of Choosey, Wisconsin) the Standard of Deviation is a kind of average of the answers that disagree with the results of the study.  The standard of deviation can tell us that as many as 2 out of 5 candidates did eat a bushel of apples and got cancer anyway.  But not always, “What about this guy who ate three bushels of apples every month for his entire life?”,  “Can’t you read?  Those were Pipins!  They’re grown in Washington.”

 

 

Copyright Prentiss Gray 2011

Prentiss Gray is a writer and columnist and currently writes the Domesti-Tech Blog for Gannett.  He can be reached through his website at www.prentissgray.com

 

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Prentiss Gray

Prentiss Gray is a writer/columnist/blogger from New Jersey. After 27 years as a Information Systems consultant and the death of his wife of 21 years, he returned to his roots as a writer, creating the national column Adventures of the Lone Dad/ Daddy chronicles. He now Blogs for Gannet on domestic technology, and writes feature pieces and stories for general publication. He is a member of the American Society of Journalists and Authors and contributes to Bloomberg News, Daily Record, Gannett and the Tribune Syndicate.

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6 comments to Clean living: Kills ‘em dead every time

  • Don Frankel

    Thank your for bringing a little ray of sunshine and good humor into this area of unending anxiety. Reminds me years ago my friends and I were out to lunch. Because we had been good customers the owner put a plate of beautiful pastry on the table for desert compliments of the house. Two guys just looked at the little items that were against their diets. One of my friends looked at their consternation and said. “If you don’t eat these, you will live an extra fifteen minutes.”

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  • mistermuse

    Reading this piqued my curiousity about the old saying, “An apple a day keeps the doctor away.” It seems that its origins can be traced back to Wales in 1866, when the February edition of Note and Queries Magazines contained this “Pembrokeshire proverb. Eat an apple on going to bed, and you’ll keep the doctor from earning his bread.” This so struck my poetic fancy that I was inspired to pen this multiple choice poem: Read a poem a day,
    and a. your blues you’ll allay. b. your troubles will go away. c. you’ll always be gay. d. your hair won’t turn gray. Personal preference aside, think twice before choosing c.

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  • Michael Crumling

    Good points Prentiss. The old saying “figures don’t lie but liars figure” comes to mind. As well, the hygiene rules we use today are not necessarily good. As you pointed out, the overuse of disinfectants and antibiotics has caused some problems. We could take a lesson from vaccines in that exposure to viruses etc causes a better physical response or resistance. To paraphrase Admiral Stockdale: “You can I am told, kill the lilies if you overpurify the lily pond”

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  • steveG

    Great post Prentiss. I don’t have much faith in medical studies, impossible to factor in all pertinent factors when we don’t even know what they are. My mom smoked until her eighties and is in her nineties now. I never get flu shots, I would rather get the flu. I believe being too clean lowers our immune sytem. I also believe extremes of any kind are bad. Being healthy goes along with being happy, which goes along with loving and being loved and being passionate about something. Luck is proably the biggest denominator.

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  • Nick Farina

    The hospitalist who attended my needs following bone marrow transplant was a specialist in immunology. He worked the night shift, from 11 pm – 7 am. One sleepless night while I was “nadiring” (0 white blood cell count), he sat by my bed and advised me to sit on the grass, clean a toilet and play with my cat as soon as I was released. He said that we are designed to interface with this world and all its microbes, even if we are immunosuppressed. He said my fears of acquiring communicable diseases were valid, but attempting to create a sterile environment would slow my recovery more than enduring occasional infections in the effort to restore a functional immune system. As I live and breathe, I do believe he was right.
    I followed his advise to a degree, washed my hands alot and never touched my face. I caught dozens of infections, mostly respiratory and digestive. I endured and treated each one appropriately. Out of 28 transplant recipients, I am one of two who is still alive. The majority who did not survive used sanitizers, bleach and antibacterial soaps in their quarantined rooms. The jury is still out.

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  • I agree with steveG about being too clean. Kids who play in dirt are usually healthy, at least mine were when young. We have to learn to live with Nature and its organisms by building immunity through exposure. I believe that flu shots work for me and my family but maybe not for others. Mothers who advocate anti- vaccinations because a few children had severe side affects are practicing their own form of medicine. Genetics play a huge role in whether a human will contract cancer. There are other factors in play such as contamination and cancer resulting from unhealed broken bones, etc.Statistics are of no use to me because every BODY is different. I was involved,as I said before, in cancer research. The Mayo Clinic has made great strides in stopping early cancers.

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